Recent media reports about acetaminophen (Tylenol) use in pregnancy and the use of Leucovorin

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Read the full update below. 

The U.S. government has recently suggested a possible link between acetaminophen use during pregnancy and autism spectrum disorder (ASD) and has promoted Leucovorin as a potential treatment for autism. This announcement has understandably caused worry among pregnant individuals and families affected by autism.

In Canada, current medical guidance continues to support the safe use of acetaminophen during pregnancy for short-term pain or fever, when used at recommended doses.

In terms of Leucovorin, the Autism Alliance of Canada notes that research into its effectiveness as a supportive intervention for autism is still in early stages, with limited evidence and small study sizes. As such, it is not currently recommended as a standard treatment by any medical authority.

CTN encourages families to seek information from trusted sources. The following are reliable sources for information on the use of Acetaminophen and Leucovorin:
 


Families with concerns should consult their health care providers for guidance tailored to their individual needs.

 


2025-10-01


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